Flights from Cartagena to Santo Domingo from $193 USD

Santo Domingo is one of the most historic and vibrant cities in the Caribbean. As the capital of the Dominican Republic, it blends its iconic Colonial Zone—recognized as a UNESCO World Heritage Site—with modern urban life, local gastronomy, and a lively cultural scene. It is the perfect destination for travelers seeking history, culture, and the authentic Caribbean rhythm all in one city.

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Santo Domingo
From May 01, 2026 to May 31, 2026
Cartagena (CTG) to Santo Domingo (SDQ)
Santo Domingo
From Jun 01, 2026 to Jun 30, 2026
Cartagena (CTG) to Santo Domingo (SDQ)
Santo Domingo
From Apr 01, 2026 to Apr 30, 2026
Cartagena (CTG) to Santo Domingo (SDQ)


Explore Santo Domingo

🌐 Santo Domingo, DO

Columbus Lighthouse

A cross-shaped monument and museum dedicated to the encounter of two worlds. (Free entry)

🌐 Santo Domingo, DO

The Three Eyes

Natural park with limestone caverns and crystal clear underground lakes. (Paid entry)

🌐 Santo Domingo, DO

Museum of the Royal Houses

16th-century historic building that housed colonial administrative institutions. (Free entry)

🌐 Santo Domingo, DO

Colonial Zone

The foundational heart of Santo Domingo, the first permanent European settlement in the Americas. (Free entry)



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